Cancer Club Meeting 2018
Minnesota Genetic Counselors Association
Tuesday July 31st, 2018
8:00 am - 4:30 pm Allina Commons - Pettingill side A
Moderators: Ashley Deckman, Lindsey Bade, Rachel Riesgraf
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This event has been approved by the National Society of Genetic Counselors (NSGC) for a 0.7 Category 1 CEUs and 7.0 Contact Hours. The American Board of Genetic Counseling (ABGC) accepts CEUs approved by NSGC for purposes of recertification.
Agenda
8:00 - 8:15 am
Breakfast (provided), Introductions, Logistics for the day
8:15 - 9:45 am
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(90 min/1.5 contact hrs)
Implications of Tumor Testing and the Role of the Genetic Counselor
Linsey Bade, PhD, MS, LGC; Megan Hanson, MS, LGC
a) Compare germline and somatic genetic testing
b) Examine available paired tumor testing, providing pertinent clinical examples
c) Evaluate the role of the clinical genetic counselor in tumor testing
9:45 - 10:45 am
(60 min/1.0 contact hrs)
Selected Review of the 7th International Symposium of Hereditary Breast and Ovarian Cancer
Shari Baldinger, MS, CGC
a) List 2 functions of BRCA1 protein and recognize at least one way tumors become resistant to PARP inhimbition
b) List 2 factors that make gene mutations "actionable" with respect to breast cancer risk
c) Determine which of the following are or are not actionable at this time: NBN, BARD1, BRIP1, MLH1, CHEK2 truncating, CHEK2 I157T, ATM, RAD51C, RAD51D
d) Describe the goal of CIMBA
e) Examine the benefit of using SNPs for more personalized risk prediction
f) Review current evidence that anti-progesterone directed breast cancer chemoprevention may be an option for BRCA1 mutation carriers
10:45 - 11:00 am
Break
11:00 am - 12:00 pm
(60 min/1.0 contact hrs)
Empiric Risk Estimates for Breast Cancer - Select Updates from the Literature
Elisabeth Wurtmann, PhD, MS, CGC
a) Review risk estimates for breast and ovarian cancer for female carriers of BRCA mutations, focusing on a critical review of Kuchenbaeker et al JAMA 2017
b) Review risk estimates for contralateral breast cancer based on a family history of breast cancer, focusing on a critical review of Reiner et al 2018 JCO
c) Facilitate group discussion regarding the use of empiric cancer risk estimates in clinical counseling
12:00 - 12:45 pm
Lunch
12:45 - 1:45 pm
(60 min/1.0 contact hrs)
SNP Based Risk Assessment Models; Panel Discussion
Ashley Deckman, MS LGC; Eric Rosenthal PhD
a) Summarize validation data for SNP based risk assessment models
b) Critique the clinical utility of SNP based risk assessment models
1:45 - 2:45 pm
(60 min/1.0 contact hrs)
Education Strategies for Genetic Counselors
Rachel Riesgraf, MS, LGC
a) Review resources available to facilitate continued education of genetic counselors in the cancer setting
b) Identify challenges and barriers that genetic counselors face in trying to remain up to date on relevant changes in the field
c) Formulate individual and group goals for local genetic counselor participation in educational efforts
2:45 - 3:00 pm
Break
3:00 - 4:30 pm
(90 min/1.5 contact hrs)
Cancer Genetics Case Conference
Moderator: Rachel Riesgraf, MS, LGC
a) Review clinical scenarios in which a pedigree and/or NGS test results presented a challenge to clear interpretation
b) Review clinical scenarios in which unique psychosocial factors impact the genetic counseling session and subsequent recommendations for testing
c) Facilitate group discussion regarding different approaches to case management in challenging situations
4:30 - 5:00 pm
Closing Comments/Evaluations